If you are here then definitely you need information about Promethazine which you will find here. Through this article, we are giving you information on the use, dosage, side effects of Promethazine along with other important points, so do read the article completely.
What is Promethazine?
Promethazine is a medication that belongs to the class of antihistamines. It is used to treat a variety of conditions, such as allergies, nausea and vomiting, motion sickness, and insomnia.
Promethazine works by blocking the effects of histamine, which is a substance produced by the body during an allergic reaction. By blocking histamine, promethazine can help alleviate symptoms such as itching, swelling, and runny nose. It also has sedative properties, which can help with insomnia and motion sickness.
Promethazine is available in various forms, including tablets, syrups, and suppositories. It is usually taken orally, but it can also be administered rectally.
Promethazine Generic Name
Promethazine is the generic name for this medication. It is also sold under various brand names, such as Phenergan, Promethegan, and Phenadoz, among others.
Promethazine Brand Name
Promethazine is sold under various brand names, some of which include:
These brand names may vary depending on the country and manufacturer.
Promethazine Knowledge Table
|Drug class||Antihistamine, antiemetic, antipsychotic|
|Uses||Treatment of allergies, nausea and vomiting, motion sickness, sedation, and anxiety|
|Dosage forms||Tablets, capsules, syrups, suppositories|
|Administration||Oral, rectal, intramuscular, intravenous|
|Common side effects||Drowsiness, dizziness, dry mouth, blurred vision, nausea, constipation|
|Serious side effects||Severe allergic reactions, irregular heartbeats, seizures, respiratory depression, neuroleptic malignant syndrome|
|Drug interactions||Alcohol, sedatives, opioids, benzodiazepines, other CNS depressants|
|Pregnancy category||C (may be acceptable in certain situations)|
|Availability||Prescription-only in most countries|
It is important to note that this table is not exhaustive and there may be other important details or considerations when using promethazine. It is always best to consult a doctor for personal advice and guidance.
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Promethazine pills are a form of medication that contain the active ingredient promethazine. They are available in different strengths, ranging from 12.5 mg to 50 mg, and may come in various shapes, sizes, and colors, depending on the manufacturer and dosage strength.
Promethazine 25mg is a dosage strength of the medication promethazine. It is a tablet that contains 25mg of the active ingredient promethazine, which is an antihistamine medication used to treat various conditions such as allergies, motion sickness, nausea and vomiting, and insomnia.
The recommended dose of promethazine 25mg may vary depending on the condition being treated and individual patient factors, such as age and weight. Generally, it is recommended to take one 25mg tablet orally every 4-6 hours as needed for symptom relief. The maximum daily dose of promethazine is usually 100mg per day.
Promethazine Cough Syrup
Promethazine cough syrup is a medication that contains promethazine and is used to treat cough and related symptoms. It is a prescription-only medication and should only be taken under the supervision of a healthcare professional.
Promethazine cough syrup is often combined with codeine, a narcotic pain reliever, to create a cough syrup that can effectively treat cough and related symptoms, such as congestion and runny nose. This combination is sometimes referred to as promethazine-codeine cough syrup.
Promethazine cough syrup works by suppressing the cough reflex and reducing inflammation in the respiratory tract. It also produces sedative effects that can help with cough-related sleep disturbances.
It is important to follow the dosing instructions provided by your doctor or pharmacist when taking promethazine cough syrup, as the dosage and frequency of administration may vary depending on the condition being treated and your individual needs.
Promethazine is available in various forms and colors, depending on the manufacturer and dosage strength. One common form of promethazine is a tablet that is yellow in color.
Yellow promethazine tablets are available in different strengths, ranging from 12.5 mg to 50 mg. They may be imprinted with the manufacturer’s logo or a code that identifies the strength of the medication. It is important to note that the color and appearance of the tablet may vary depending on the manufacturer, so it is always best to check the label or consult with a healthcare professional to confirm the correct medication and dosage.
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Promethazine hydrochloride is the hydrochloride salt form of the medication promethazine. It is a crystalline solid that is white or slightly yellow in color, and it is soluble in water and alcohol.
Promethazine hydrochloride is commonly used in the formulation of oral tablets, injections, and topical preparations of promethazine. The hydrochloride salt form of promethazine is often preferred because it is more stable than the base form and has better water solubility, which makes it easier to dissolve in water-based formulations.
Like promethazine, promethazine hydrochloride is an antihistamine medication that is used to treat various conditions, such as allergies, motion sickness, and nausea and vomiting. It is important to follow the dosing instructions provided by your doctor or pharmacist when taking promethazine hydrochloride.
Promethazine dextromethorphan is a combination medication that contains two active ingredients: promethazine and dextromethorphan. It is commonly used to treat cough and related symptoms, such as congestion and runny nose.
Promethazine is an antihistamine medication that works by reducing the effects of histamine, a substance produced by the body during an allergic reaction, and by producing sedative effects that can help with cough-related sleep disturbances. Dextromethorphan is a cough suppressant medication that works by suppressing the cough reflex in the brain.
Combining these two medications can provide a more effective treatment for cough and related symptoms than either medication alone.
It is important to follow the dosing instructions provided by your doctor or pharmacist when taking promethazine dextromethorphan, as the dosage and frequency of administration may vary depending on the condition being treated and your individual needs.
Promethazine is a medicine that is used to treat a variety of conditions, including:
- Allergies: Promethazine can be used to relieve symptoms of seasonal allergies, such as sneezing, itching, and runny nose.
- Motion sickness: Promethazine can help prevent nausea and vomiting associated with motion sickness.
- Nausea and vomiting: Promethazine can be used to relieve nausea and vomiting caused by various conditions, such as chemotherapy, surgery, or gastrointestinal disorders.
- Insomnia: Promethazine can produce sedative effects that can help with sleep disturbances.
- Cough: Promethazine can be combined with other medications, such as codeine or dextromethorphan, to treat cough and related symptoms.
- Anxiety: Promethazine can be used to relieve anxiety and produce a calming effect.
It is important to note that promethazine should only be used under the guidance of a doctor and should not be used for self-treatment.
Who should not use Promethazine?
Promethazine is an antihistamine medication used for the treatment of various conditions such as allergic reactions, nausea and vomiting, motion sickness, and sedation. However, not everyone can safely use promethazine.
Individuals with the following conditions should not use promethazine:
- Hypersensitivity to promethazine or any of its components
- Respiratory depression
- Asthma or other lower respiratory tract conditions
- Severe central nervous system depression
- Liver disease
- Bone marrow suppression
- Reye’s syndrome or suspected cases of Reye’s syndrome
- Epilepsy or seizure disorders
- Cardiovascular disease, such as heart disease, hypertension, or arrhythmias.
It is important to always consult with a healthcare provider before taking promethazine or any other medication to ensure its safety and appropriateness for your specific condition.
What should not be taken with Promethazine?
Promethazine can interact with other medicines, which can lead to some harmful effects. Some drugs should not be taken with promethazine. Here are some examples:
- Alcohol: Avoid consuming alcohol while taking promethazine, as this can increase the sedative effects of the medication and lead to respiratory depression.
- CNS Depressants: Avoid using other medications that have a sedative effect, such as benzodiazepines, opioids, or barbiturates, while taking promethazine. These medications can increase the sedative effects of promethazine and lead to respiratory depression or coma.
- Anticholinergics: Avoid using medications that have anticholinergic effects, such as some antidepressants, antihistamines, or medications for urinary incontinence, while taking promethazine. These medications can increase the risk of side effects, such as dry mouth, blurred vision, constipation, and urinary retention.
- MAO inhibitors: Avoid using medications that are MAO inhibitors, such as some antidepressants or Parkinson’s disease medications, while taking promethazine. These medications can increase the risk of serious side effects, such as hypertensive crisis or serotonin syndrome.
- Epinephrine: Promethazine can interfere with the action of epinephrine, a medication used to treat severe allergic reactions. Therefore, promethazine should not be used to treat anaphylaxis or other severe allergic reactions.
Be sure to inform your doctor about all the drugs, supplements, and herbal products you are taking before starting promethazine or any other medicine. They can advise you on how you can take these things with your medicine.
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The dose of promethazine may vary depending on the condition being treated and individual patient factors, such as age, weight, and overall health. It is important to follow the dosage instructions given by your doctor.
Here are some general guidelines for the dosing of promethazine:
- Allergies: The recommended dose for adults is 25mg to 50mg orally every 4 to 6 hours as needed. For children, the recommended dose is based on weight and usually ranges from 6.25mg to 12.5mg every 4 to 6 hours as needed.
- Motion sickness: The recommended dose for adults is 25mg orally every 4 to 6 hours as needed. For children, the recommended dose is based on weight and usually ranges from 6.25mg to 12.5mg every 4 to 6 hours as needed.
- Nausea and vomiting: The recommended dose for adults is 12.5mg to 25mg orally every 4 to 6 hours as needed. For children, the recommended dose is based on weight and usually ranges from 6.25mg to 12.5mg every 4 to 6 hours as needed.
- Insomnia: The recommended dose for adults is 25mg to 50mg orally at bedtime. For children, the recommended dose is based on weight and usually ranges from 6.25mg to 12.5mg at bedtime.
- Cough: The recommended dose of promethazine for cough may vary depending on the specific formulation and other active ingredients. It is important to follow the dosing instructions provided by your doctor or pharmacist.
- Anxiety: The recommended dose for adults is 25mg to 50mg orally every 4 to 6 hours as needed.
It is important not to exceed the maximum daily dose of 100 mg per day for promethazine and to be aware of the potential side effects of the drug. If you have any questions regarding the dosage or use of promethazine, be sure to consult with your doctor.
Promethazine Overdose Symptoms
An overdose of promethazine can be very serious and may require immediate medical attention. The following are some symptoms of promethazine overdose:
- Severe drowsiness or sedation
- Confusion or disorientation
- Agitation or restlessness
- Hallucinations or delusions
- Slow or shallow breathing
- Respiratory depression (very slow or stopped breathing)
- Low blood pressure
- Irregular heartbeat
If you suspect that you or someone else may have taken too much promethazine, it is important to seek immediate medical attention.
Promethazine Side Effect
Like all other medicines promethazine has some side effects.
Following are some of the common side effects of Promethazine –
- Dry mouth
- Blurred vision
- Nausea and vomiting
- Muscle weakness
- Tremors or shaking
- Skin rash or itching
Less common but more serious side effects of promethazine may include:
- Severe allergic reactions (swelling of the face, lips, tongue or throat, difficulty breathing or hives)
- Irregular heartbeats
- Respiratory depression (very slow or stopped breathing)
- Neuroleptic malignant syndrome (a potentially life-threatening reaction that can cause fever, muscle stiffness, confusion and other symptoms)
Get immediate medical attention if you experience any of these serious side effects. In general, be aware of the potential side effects of any medication and be sure to talk to your doctor if you have any concerns.
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Promethazine Withdrawal Symptoms
Promethazine is not generally associated with physical dependence or withdrawal symptoms, as it is not considered an addictive substance. However, sudden discontinuation or rapid reduction of high doses of promethazine can cause some withdrawal-like symptoms, such as:
- Muscle cramps
It is important to note that these symptoms are usually not serious and usually go away within a few days to a week. If you are taking promethazine and plan to stop using it, be sure to consult with your doctor.
Through this article, our aim is to provide correct and appropriate information about Promethazine to you. We hope that you have got complete information related to Promethazine through this article and this has increased your knowledge about medicines. Through this website of ours, we keep bringing information about various such medicines to you. If you want to get information about any other medicine, then you can get it by visiting the Home Page of our website.
FAQ: Related to Promethazine
1. Does Promethazine make you sleepy?
Yes, promethazine can cause drowsiness as a common side effect. It is an antihistamine that can also be used as a sedative, and its sedative properties may contribute to the drowsiness.
2. Is Promethazine same as Benadryl?
Promethazine and Benadryl are both antihistamines that can be used to treat allergies, but they have different chemical structures and may have different side effects and uses.
3. Does Promethazine have codeine in it?
Some formulations of promethazine may contain codeine, which is an opioid pain reliever. However, not all promethazine products contain codeine, and it is important to read the label or consult with a healthcare professional.
4. Is 50 mg Promethazine too much?
The appropriate dose of promethazine depends on various factors, such as the intended use, age, weight, and overall health of the individual. A dose of 50 mg may be too much for some individuals and should be determined by a healthcare professional.
5. What organ does Promethazine effect?
Promethazine affects various organs in the body, including the brain, gastrointestinal system, and cardiovascular system. It works by blocking certain receptors, such as histamine and dopamine receptors, and can have sedative and antiemetic effects.
6. How much Promethazine is sedative?
The sedative effects of promethazine can vary depending on various factors such as the dose, age, weight, and overall health of the individual. Higher doses of promethazine are more likely to cause sedation than lower doses.
7. What drugs should not be taken with Promethazine?
Promethazine may interact with various drugs, such as alcohol, sedatives, opioids, benzodiazepines, and other central nervous system depressants. Taking promethazine with these drugs may increase the risk of sedation, respiratory depression, and other side effects.
8. Is Promethazine a controlled substance?
Promethazine is not classified as a controlled substance by the United States Drug Enforcement Administration (DEA). However, it is a prescription-only medication and may have abuse potential in certain situations.
Note – Please note that all the information given in this article is given for the purpose of education. Before using this medicine in any way, you must consult a qualified doctor.